A Review on Innovative Drug Delivery Platforms
DOI:
https://doi.org/10.61427/jcpr.v4.i1.2024.120Keywords:
Drug Delivery, Lipid-Based Drug Delivery Systems, Targeted Drug DeliveryAbstract
In recent years, the field of drug delivery has undergone a transformative shift with the introduction of innovative platforms that transcend conventional methods, providing accurate and efficient means for delivering therapeutic agents. This exploration delves into the distinctive features and potential impacts of these pioneering platforms, charting a course for the future of pharmaceutical interventions. In this review article, the advancements regarding the nanotechnology-enabled delivery, lipid-based drug delivery systems, targeted drug delivery, implantable drug delivery systems, 3D printing in drug delivery, stimuli-responsive delivery systems, mRNA and gene delivery platforms and microfluidic - based delivery systems were discussed. These innovative drug delivery platforms represent a dynamic frontier in pharmaceutical research and development. They afford unprecedented control over drug properties, release kinetics and targeting strategies. As research continues to push the boundaries of drug delivery science, these innovations hold the potential to revolutionize the treatment of various diseases, ushering in safer, more effective and patient-centric therapeutic solutions.
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Nafiu A, Salim I, Mohammed Al-Kassim Hassan, Fatima SK, Abubakar IJ, Siok-Yee Chan, Deghinmotei Alfred-Ugbenbo. Applications of nanofibers drug delivery system in cancer therapy. Journal of Drug Delivery Science and Technology, 2023; 90: 105128.
Preeti S, Sankha Bhattacharya, Sateesh B, Bhupendra GP, Gehan M. The theranostic potential of green nanotechnology-enabled gold nanoparticles in cancer: A paradigm shift on diagnosis and treatment approaches. Results in Chemistry, 2024; 7: 101264.
Akila Kesavan U, Chandrasekhar Reddy, Jais Kurian. Cancer cell uptake and distribution of oxanorbornane-based synthetic lipids and their prospects as novel drug delivery systems. Journal of Drug Delivery Science and Technology, 2022; 23: 103439.
Raza F, Zheng M, Zhong H, Su J, He B, Yuan WE, Qiu M. Engineered tumor microvesicles modified by SP94 peptide for arsenic trioxide targeting drug delivery in liver cancer therapy. Biomater Adv. 2023 Dec; 155: 213683.
Capacio BA, Shankara Narayanan JS, Vicente DA, Liu Y, LaPorte JP, Cox BF, Jaroch DB, Katz SC, White RR. Pressure-Enabled Drug Delivery (PEDD) of a class C TLR9 agonist in combination with checkpoint inhibitor therapy in a murine pancreatic cancer model. Surgery. 2023 Sep; 174(3):666-73.
Zaer M, Moeinzadeh A, Abolhassani H, Rostami N, Tavakkoli Yaraki M, Seyedi SA, Nabipoorashrafi SA, Bashiri Z, Moeinabadi-Bidgoli K, Moradbeygi F, Farmani AR, Hossein-Khannazer N. Doxorubicin-loaded Niosomes functionalized with gelatine and alginate as pH-responsive drug delivery system: A 3D printing approach. Int J Biol Macromol. 2023 Dec 31; 253(Pt 2):126808.
Kim HS, Kang JH, Jang J, Lee EJ, Kim JH, Byun J, Shin US. Dual stimuli-responsive mesoporous silica nanoparticles for efficient loading and smart delivery of doxorubicin to cancer with RGD-integrin targeting. Eur J Pharm Sci. 2023 Sep 1; 188: 106525. doi: 10.1016/j.ejps.2023.106525.
Jin Y, Yu W, Zhang W, Wang C, Liu Y, Yuan WE, Feng Y. A novel fluorinated polyethyleneimine with microRNA-942-5p-sponges polyplex gene delivery system for non-small-cell lung cancer therapy. J Colloid Interface Sci. 2023 Oct 15; 648:287-298. doi: 10.1016/j.jcis.2023.05.153.
Xiang Chen, Danna Liang, Weijian Sun, Xin Shou, Luoran Shang, Xian Shen. Suspended bubble microcapsule delivery systems from droplet microfluidic technology for the local treatment of gastric cancer. Chemical Engineering Journal, 2023; 458: 141428.
Sanjeev Gautam, Ishita Lakhanpal, Lidiya Sonowal, Navdeep Goyal. Recent advances in targeted drug delivery using metal-organic frameworks: Toxicity and release kinetics. Next Nanotechnology, 2023: 100027.
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