A Brief Review on Rabbit Syndrome

Authors

  • Jyothi Bonam Clinical Pharmacist, ECHS Polyclinic, Vijayawada, Andhra Pradesh, India.

DOI:

https://doi.org/10.61427/jcpr.v1.i1.2021.5

Keywords:

Antipsychotics, Olanzapine, Rabbit Syndrome

Abstract

Rabbit syndrome is a rare condition affecting only a small amount of psychiatric patients who are under antipsychotic treatment. This syndrome is characterized by fine, rapid, rhythmic movements along the vertical axis of mouth accompanied by lip sound and these movements occur with a frequency of approximately 5Hz. This syndrome is a late onset extra pyramidal side effect occurring 2- 5% of patients who were chronically treated with neuroleptics. Usually it occurs more in females older than 40years and twice predominant than males. Providing the empirical treatment by considering the neuropathological aspects of the patients may enhance the quality of life. To improve the treatment options, advanced research on the neurophysiological and pharmacological aspects are required.

Downloads

Download data is not yet available.

References

Catena M, Fagiolini A, Consoli G. The rabbit syndrome: State of the art. Curr Clin Pharmacol. 2007; 2: 212-6.

Villeneuve A. The Rabbit Syndrome-A peculiar extra pyramidal reaction. Can Psychiatr Assoc J. 1972; 17(2): 69-72.

Catena DM, Fagiolini A, Ducci F, Masalehdan A, Ciapparelli A, Frank E. Newer antipsychotics and the rabbit syndrome. Clin Pract Epidemiol Ment Health. 2007; 3:6.

Deshmukh D, Joshi V, Agarwal M. Rabbit Syndrome - A Rare Complication of Long term Neuroleptic Medication. Br J Psychiatry. 1990; 157(2): 293.

Schwartz M, Hocherman S. Antipsychotic induced rabbit syndrome: Epidemiology, management and Pathophysiology. CNS Drugs. 2004; 18(4): 213-20.

Jus K, Jus A, Gautier J, Villeneuve A, Pires P, Pineau R, Villeneuve R. Studies on the action of certain pharmacological agents on tardive dyskinesia and on the rabbit syndrome. Int J Clin Pharmacol. 1974; 9:138-45.

Sovner R, Dimascio A. The effect of benztropine mesylate in the rabbit syndrome and tardive dyskinesia. Am J Psychiatry. 1977; 134: 1301-2.

Jus K, Jus A, Villeneuve A, Villeneuve R. Influence of concentration and motor performance on tardive dyskinesia and rabbit syndrome. Can Psychiatr Assoc J. 1973; 18: 327-30.

Jus K, Villeneuve A, Jus A. Tardive dyskinesia and the rabbit syndrome during wakefulness and sleep. Am J Psychiatry. 1972; 129 (6): 765.

Schwartz M, Weller B, Erdreich M, Sharf B. Rabbit syndrome and tardive dyskinesia: Two complications of chronic neuroleptic treatment. J Clin Psychiatry. 1995; 56 (5): 212.

Durst R, Katz G, Zislin J, Raskin S, Kalman I. Rabbit syndrome treated with olanzapine. Br J Psychiatry. 2000; 176:193.

Altindag A, Yanik M. A case of rabbit sindrome treated with quetiapine. Eur Psychiatry. 2005; 20: 574-75.

Tarsy D, Baldessarini RJ, Tarazi FI. Effects of newer antipsychotic on extrapyiramidal function. CNS Drugs. 2002; 16: 23-45.

Published

2021-01-14
Statistics
232 Views | 171 Downloads
Citatons

How to Cite

Bonam, J. “A Brief Review on Rabbit Syndrome”. Journal of Clinical and Pharmaceutical Research, vol. 1, no. 1, Jan. 2021, pp. 4-5, doi:10.61427/jcpr.v1.i1.2021.5.

Issue

Section

Review Articles