A Study on the Assessment of Risk in the Management of Acute Coronary Syndrome using GRACE score

Authors

  • Nikhil Chandra H Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar, Telangana, India.
  • Sindhuja Govula Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar, Telangana, India.
  • Buyyani Swathi Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar, Telangana, India.
  • P Soumya Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar, Telangana, India.

Keywords:

Acute Coronary Syndrome, Myocardial Infarction, Percutaneous Coronary Intervention

Abstract

Aim: To assess the risk in the management of acute coronary syndrome by using GRACE score.

Methods: This was an observational study conducted among 155 patients of cardiology department. Myocardial infarction patients of age above 20 years who were treated with fibronolytics were included in the study. Patients were assessed for the risk by using the GRACE (Global Registry of Acute Coronary Events) score criteria and was classified into low (?108 points), intermediate (109 to 140 points) and high (>140 points).

Results: In this study, the severity of the LV dysfunction in most of the patients was observed to be mild followed moderate and severe. Majority of the patients were observed to be with high risk 61 (39.35%) followed by low risk 49 (31.61%) and intermediate risk 45 (29.04%). Most of the patients with high risk were observed to be in the age group 61-70 years (26.23%) whereas with intermediate risk were observed to be in the age group 41-50 years (35.55%).

Conclusion: Among the mild, moderate and severe LV dysfunction, most of the patients were observed to be with high risk according to the GRACE score criteria.

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References

Basit H, Malik A, Huecker MR. Non–ST-Segment Elevation Myocardial Infarction. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan PMID: 30020600.

James, Stefan, and Hector Bueno (ed.), 'Epidemiology of acute coronary syndromes', The ESC Textbook of Cardiovascular Medicine, 3 edition, The European Society of Cardiology Series; Oxford, 2018; ESC Publications.

Textbook of pathology, 6th edition, Harsh Mohan, chapter-16, pg no: 429.

Davidson’s principles and practice of medicine, 22nd edition, chapter-18, pg no: 595.

Rama M, Miraci M, Petrela E, Malaj L. Comparison of reteplase double bolus administration with streptokinase in acute myocardial infarction. Int J Pharm Sci. 2015; 7(6):180-3.

Published

2023-07-17
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How to Cite

Nikhil Chandra H, Sindhuja Govula, Buyyani Swathi, and P Soumya. “A Study on the Assessment of Risk in the Management of Acute Coronary Syndrome Using GRACE Score”. Journal of Clinical and Pharmaceutical Research, vol. 3, no. 3, July 2023, pp. 11-14, https://jcpr.in/index.php/journal/article/view/90.

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Section

Research Articles