Precision Pharmacogenomics: A Review

Authors

  • Slesha Kumar Kosuru Department of Pharmaceutical Analysis & Quality Assurance, Lydia College of Pharmacy, Ravulapalem, Andhra Pradesh, India.
  • Santhosh Kumar Gandham Department of Pharmaceutical Analysis & Quality Assurance, Lydia College of Pharmacy, Ravulapalem, Andhra Pradesh, India.
  • Bhagya Naga Lakshmi Siripalli Department of Pharmaceutical Analysis & Quality Assurance, Lydia College of Pharmacy, Ravulapalem, Andhra Pradesh, India.
  • K.V.S.S. Annapurna Department of Pharmaceutical Analysis & Quality Assurance, Lydia College of Pharmacy, Ravulapalem, Andhra Pradesh, India.
  • D. Vinoothna Department of Pharmaceutical Analysis & Quality Assurance, Lydia College of Pharmacy, Ravulapalem, Andhra Pradesh, India.
  • D. Vaishnavi Department of Pharmaceutical Analysis & Quality Assurance, Lydia College of Pharmacy, Ravulapalem, Andhra Pradesh, India.

DOI:

https://doi.org/10.61427/jcpr.v4.i1.2024.121

Keywords:

Genetics, Genomic Medicine, Pharmacogenomics

Abstract

Embarking on precision pharmacogenomics journey is a transformative experience in the world of medicine. This innovative approach, distinct from traditional practices tailors treatments to each individual's unique genes. Unlike standard methods where everyone gets the same medicine, precision pharmacogenomics uses a person's genetic information as an approach to determine the most effective treatment. In this personalized medical adventure, the individual's genes act like a guide for healthcare providers. Moreover, there is a growing focus on ensuring equitable access to personalized medicine. Efforts to address healthcare disparities and promote inclusivity in genomic research are expected to take center stage. Ethical considerations and robust regulatory frameworks will play pivotal roles in guiding the responsible and transparent application of precision pharmacogenomics. The future of precision pharmacogenomics promises a healthcare landscape where treatments are finely tuned to the unique genetic makeup of each individual. This forward-looking perspective suggests a future characterized by enhanced effectiveness, reduced side effects and a more inclusive approach to personalized healthcare.

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References

Youssef MR et al. Cardio-metabolic genomics and pharmacogenomics investigations in Filipino Americans: Steps towards precision health and reducing health disparities American Heart Journal Plus: Cardiology Research and Practice, 2022; 15: 100136.

Robert GM et al. Randomized trial of personalized psychological feedback from a longitudinal online survey and simultaneous evaluation of randomized stepped wedge availability of in-person peer support for hospital staff during the COVID-19 pandemic, General Hospital Psychiatry, 2023; 84: 31-38.

Meng He et al Genetic testing decision-making experiences within families of colorectal cancer patients: A qualitative study European Journal of Oncology Nursing, 2023; 66: 102417.

Ying Chen et al. Personalized symptom clusters that predict depression treatment outcomes: A replication of machine learning methods. Journal of Affective Disorders Reports. 2023; 11: 100470.

Aashiq Hussain Bhat, Umer Majeed Khaja et al. Pharmacogenomics in cancer. Pharmacogenomics from discovery to clinical implementation 2023; 195-221.

Edward PH et al. Aligning quality and payment for heart failure care: Defining the challenges. Journal of Cardiac Failure. 2003; 9(4): 251-254.

Gayathri Vaidyanathan et al. Redefining Clinical Trials: The Age of Personalized Medicine. Cell, 2012; 148(6): 1079-1080.

Ann MM et al. Translating Pharmacogenomic Research to Therapeutic Potentials (Bench to Bedside). Comprehensive Pharmacology, 2022; 2: 220-246.

Published

2024-01-13
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How to Cite

Kosuru, S. K. ., S. K. . Gandham, B. N. L. . Siripalli, K. . Annapurna, D. . Vinoothna, and D. . Vaishnavi. “Precision Pharmacogenomics: A Review”. Journal of Clinical and Pharmaceutical Research, vol. 4, no. 1, Jan. 2024, doi:10.61427/jcpr.v4.i1.2024.121.

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Review Articles

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